This Spinach Chicken Casserole with Cream Cheese and Mozzarella is a creamy, savory, and incredibly easy dinner that’s perfect for busy nights. With tender chicken breasts coated in a rich cream cheese mixture, wilted spinach, and melted mozzarella, this dish brings comfort food to the next level. It’s quick to make and deliciously satisfying, offering a perfect balance of creamy, cheesy, and savory flavors!

Why You’ll Love This Recipe

This spinach chicken casserole is an absolute winner when it comes to quick, easy, and tasty dinners. The combination of creamy cream cheese, flavorful spinach, and melty mozzarella cheese creates a luscious, comforting dish that’s bound to please everyone. The chicken is marinated with garlic and Italian seasoning, adding an extra layer of flavor before it’s baked to juicy perfection. It’s a fantastic low-carb or keto-friendly option, and the entire meal can be prepared in under an hour! Whether for a busy weeknight or a family dinner, this casserole is guaranteed to be a hit. Spinach Chicken Casserole with Cream Cheese and Mozzarella

Ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

2 large boneless, skinless chicken breasts, cut horizontally
8 oz cream cheese, softened
2 cups spinach, rinsed
2 tablespoons olive oil, divided
4 oz mozzarella cheese, shredded
3 cloves garlic, minced
1/2 teaspoon red pepper flakes (optional)
1/2 teaspoon salt
1/2 teaspoon black pepper
1/2 teaspoon Italian seasoning (optional)

Directions

In a Ziplock bag, combine 1 tablespoon olive oil, garlic, Italian seasoning, red pepper flakes, salt, and pepper. Seal the bag and shake to mix. Add the chicken breasts to the bag, seal, and massage until the chicken is evenly coated. Let the chicken marinate for 10-15 minutes on the counter while you prep the rest of the ingredients.
Preheat the oven to 400°F (200°C) and position a rack in the center.
In a skillet, wilt the spinach with 1 tablespoon olive oil over medium heat for 2–3 minutes, then set it aside.
Arrange the marinated chicken breasts in a baking dish. Spread the softened cream cheese evenly over the chicken, then layer the wilted spinach on top. Sprinkle the shredded mozzarella cheese over the spinach.
Bake the casserole for 20–30 minutes, or until the chicken reaches an internal temperature of 165°F (75°C).
Serve the casserole warm with a side of cauliflower rice or baked veggies. Enjoy!

Servings and timing

Servings: 6 servings
Prep Time: 10 minutes
Cooking Time: 30 minutes
Total Time: 40 minutes

Storage/Reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days. To reheat, simply microwave the casserole or place it in the oven at 350°F (175°C) for 10–15 minutes until heated through. The dish can also be frozen for up to 3 months. Thaw in the refrigerator overnight and reheat as needed.

FAQs

Can I use frozen spinach instead of fresh spinach?

Yes, you can use frozen spinach, but be sure to thaw and drain it well before using it in the casserole to avoid excess moisture.

Can I use chicken thighs instead of chicken breasts?

Yes, chicken thighs will work just as well. They will add a little extra richness to the dish, and you should follow the same cooking instructions for internal temperature.

Can I use a different cheese instead of mozzarella?

Yes, you can swap mozzarella for other cheeses like cheddar, provolone, or even a blend of cheeses. The flavor profile will change a bit, but it will still be delicious!

Can I make this casserole ahead of time?

Absolutely! You can prepare the casserole in advance and store it in the refrigerator for up to 1 day before baking. When ready to cook, just bake it as directed.

Is this recipe suitable for a keto diet?

Yes, this casserole is low in carbs and keto-friendly, especially when served with a side of cauliflower rice or steamed veggies.

Can I add more vegetables to the casserole?

Certainly! You can add vegetables like mushrooms, bell peppers, or onions to the casserole. Just sauté them before adding them to the dish to ensure they cook properly.

How do I know when the chicken is cooked through?

The chicken is done when it reaches an internal temperature of 165°F (75°C). A meat thermometer is the most reliable way to check for doneness.

Can I make this dish dairy-free?

To make this casserole dairy-free, use a dairy-free cream cheese alternative and a dairy-free mozzarella-style cheese. You may also need to adjust the flavors with additional herbs or seasoning to suit your tastes.

Can I use a different oil instead of olive oil?

Yes, you can substitute olive oil with another cooking oil, such as avocado oil, coconut oil, or vegetable oil.

What can I serve with this casserole?

This casserole pairs wonderfully with a side of roasted vegetables, cauliflower rice, or a fresh green salad for a complete meal.

Conclusion

This Spinach Chicken Casserole with Cream Cheese and Mozzarella is a perfect option for a comforting yet healthy dinner that comes together quickly and easily. It’s creamy, savory, and full of flavor, with tender chicken, delicious spinach, and melted cheese that everyone will love. Whether you’re cooking for a busy weeknight or preparing a family-friendly meal, this casserole is guaranteed to impress. It’s a simple, satisfying dish that fits into many dietary preferences, making it a go-to recipe in your collection!