If you are looking for a cozy, creamy, and downright delicious way to enjoy chicken, then the Spinach Artichoke Chicken Casserole Recipe is the perfect dish to add to your dinner rotation. This casserole brings together tender chicken, vibrant spinach, flavorful artichokes, and a blend of cheeses all baked to golden, bubbly perfection. It’s a fantastic crowd-pleaser that combines the comforting charm of a casserole with the fresh, vibrant flavors of classic spinach artichoke dip, making mealtime both easy and special.

Ingredients You’ll Need

A clear glass bowl sits on a white marbled surface, filled with a creamy, smooth white mixture that is evenly whipped, creating soft swirls and peaks on the top layer. The bowl shows streaks of the cream on the inside edges, adding texture to the otherwise smooth surface. Behind the bowl, there is a black and white striped cloth that is casually draped, adding a soft contrast to the scene. photo taken with an iphone --ar 4:5 --v 7

The beauty of this Spinach Artichoke Chicken Casserole Recipe is how straightforward and comforting the ingredients are. Each one plays a crucial role in creating the creamy texture, savory flavors, and luscious richness that make this dish so addictive.

1 lb. short pasta (rigatoni, ziti, or penne): Provides a hearty base that holds the creamy sauce beautifully.
2 cups cubed cooked chicken: Tender protein that soaks up all the delicious flavors.
8 oz. cream cheese (softened): Adds a dreamy, velvety texture and tangy richness.
3/4 cup sour cream (full fat or Greek yogurt): Contributes a pleasant tang and creaminess to the sauce.
3/4 cup heavy cream: Makes the casserole luscious and smooth.
1/2 cup whole milk: Balances the creaminess without weighing the dish down.
1/2 small onion, diced: Adds a subtle sweetness and depth of flavor.
1 1/2 cups shredded mozzarella (divided): Provides gooey melted cheese and a golden crust.
1/2 cup grated Parmesan: Brings a nutty, salty punch to the casserole.
10 oz. frozen spinach, thawed and drained: Packs vibrant color and nutritious greens into every bite.
1 can (14 oz.) chopped artichokes: Introduces a tender, slightly tangy complexity.
3-4 garlic cloves: Infuses the dish with aromatic warmth and flavor.
1/2 tsp red pepper flakes: Adds a subtle kick to elevate the savory notes.
1/2 tsp sea salt (or to taste): Essential for enhancing all the flavors.
1/2 tsp black pepper: Provides a gentle seasoning and balance.

How to Make Spinach Artichoke Chicken Casserole Recipe

Step 1: Prepare the Pasta

Start by preheating your oven to 350°F. Cook the pasta according to the package instructions, but be sure to stop about one minute before it reaches al dente. This ensures the pasta won’t become mushy during baking, keeping a nice bite in your casserole.

Step 2: Mix the Creamy Base

While your pasta cooks, combine the softened cream cheese and sour cream in a mixing bowl. Use an electric mixer for a few minutes until the mixture is perfectly smooth and creamy. Add the heavy cream and continue beating until fully combined. Finally, stir in the milk for a silky, luscious sauce that will coat every piece of pasta beautifully.

Step 3: Combine the Core Ingredients

Next, add the cooked chicken, thawed and drained spinach, chopped artichokes, 1 cup of mozzarella, grated Parmesan, diced onion, minced garlic, and spices (red pepper flakes, sea salt, and black pepper) to the creamy mixture. Stir everything together gently so all the flavors meld and the ingredients are evenly distributed.

Step 4: Assemble the Casserole

Drain the pasta and transfer it to a 9×13 inch baking dish lightly sprayed with oil to prevent sticking. Pour the spinach and artichoke chicken mixture over the pasta and stir until every piece is coated in the creamy sauce. Smooth it out, then sprinkle the remaining mozzarella cheese evenly on top for that irresistible golden cheese crust.

Step 5: Bake to Perfection

Bake your casserole in the oven for about 25 minutes, checking after 20 minutes to make sure the cheese on top is melting beautifully and the casserole is bubbling around the edges. If you want a crispy, bubbly golden-brown finish, pop the casserole under the broiler for the last 2 minutes — trust me, it’s worth it!

Step 6: Let It Rest Before Serving

Once baked, let your Spinach Artichoke Chicken Casserole rest for 5 to 10 minutes. This short cooling time helps the casserole set nicely, making it easier to scoop and intensifying the flavors as it finishes mingling together.

How to Serve Spinach Artichoke Chicken Casserole Recipe

A close-up view of a white bowl filled with a pasta dish, showing three main layers: a creamy white sauce mixed with pieces of light chicken and dark green spinach, rigatoni pasta with a pale yellow color, and melted cheese with a slightly browned top, sprinkled with chopped fresh parsley. A fork picks up a piece of stuffed pasta with chicken and spinach, highlighting the creamy and soft textures. The bowl sits on a white marbled surface with a blurred striped cloth in the background. photo taken with an iphone --ar 4:5 --v 7

Garnishes

To elevate your serving, sprinkle freshly chopped parsley or basil on top right before serving for a pop of color and fresh herbal brightness. A light drizzle of high-quality olive oil or a squeeze of lemon juice can also brighten the dish and add a subtle zing that complements the rich creaminess.

Side Dishes

This casserole is quite hearty on its own, but light, crisp sides pair wonderfully to balance the meal. Consider a simple arugula salad with lemon vinaigrette, roasted cherry tomatoes, or steamed asparagus with a touch of garlic and lemon. These sides add freshness and texture contrast that will round out your dinner perfectly.

Creative Ways to Present

For casual family dinners, serve this casserole straight from the baking dish with soft dinner rolls on the side. For gatherings or potlucks, spoon the casserole into individual ramekins and sprinkle extra Parmesan on top, then broil briefly for individual golden tops. You can also serve with a sprinkle of red pepper flakes to customize the spice level at the table.

Make Ahead and Storage

Storing Leftovers

Once cooled, cover your leftover Spinach Artichoke Chicken Casserole tightly with foil or plastic wrap and refrigerate. It keeps well in the fridge for up to 3 days without losing its creamy texture or flavor.

Freezing

This casserole freezes beautifully for up to 2 months. To freeze, prepare the casserole but do not bake. Wrap it tightly with foil and then plastic wrap for extra protection, or place in an airtight container. When ready, thaw overnight in the fridge and bake as directed, adding a few extra minutes as needed.

Reheating

To reheat, bake leftovers in a preheated 350°F oven for about 15-20 minutes, or until heated through and bubbly. Cover with foil to prevent the cheese from over-browning unless you want a crispier top. Alternatively, microwave individual servings covered for a faster option, though the oven method better preserves texture and flavor.

FAQs

Can I use fresh spinach instead of frozen?

Absolutely! If using fresh spinach, sauté it lightly until just wilted, then drain any excess moisture to prevent the casserole from becoming watery. Frozen spinach is convenient and consistent, but fresh adds a lovely, vibrant flavor.

What type of chicken works best for this casserole?

Cooked, shredded or cubed chicken works best. You can use leftover roasted chicken, rotisserie chicken, or quickly pan-cook chicken breasts or thighs. Using pre-cooked chicken speeds up preparation and ensures tender bites throughout.

Is there a vegetarian version of this recipe?

Yes! Simply omit the chicken and consider adding more artichokes or mushrooms for texture and flavor. You can also add cooked lentils or chickpeas to boost protein while keeping it vegetarian-friendly.

How spicy is the casserole with red pepper flakes?

The 1/2 teaspoon of red pepper flakes adds just a gentle warmth that enhances the dish without making it spicy-hot. You can adjust or omit according to your family’s preferences.

Can I make this recipe gluten-free?

Definitely! Use your favorite gluten-free pasta instead of regular pasta. Make sure all other ingredients (like cream cheese and sour cream) are labeled gluten-free, and you’ll have a delicious gluten-free Spinach Artichoke Chicken Casserole Recipe.

Final Thoughts

There is something truly comforting about a casserole that wraps up creamy, cheesy goodness with nutritious greens and hearty chicken, and this Spinach Artichoke Chicken Casserole Recipe hits every note perfectly. Whether it’s a weeknight dinner or a special occasion, this dish brings warmth, satisfaction, and plenty of smiles to the table. I can’t wait for you to try it and see just how effortlessly delicious it is!