Name: One Pot Creamy Cajun Chicken Pasta Recipe
Prep time: 10 min
Cook time: 20 min
Total time: 30 min
Cuisine: American
Ingredients: 2 tsp smoked paprika; 1 tsp oregano; 1 tsp thyme; 1/2 tsp garlic powder; 1/2 tsp onion powder; 1/4 tsp cayenne pepper; 1/4 tsp black pepper; 1/4 tsp salt; 1 Tbsp olive oil; 1 Tbsp butter; 1 lb. boneless, skinless chicken breast, cut into 1/2 to 3/4-inch cubes; 1 yellow onion, diced; 1/2 lb. penne pasta (uncooked); 15 oz. fire roasted diced tomatoes, with juices; 2 cups chicken broth; 2 oz. cream cheese; 3 green onions, sliced

Jump to Recipe· 4.3 from 13 reviews

If you are looking for a dish that brings bold Southern flavor and creamy comfort together in one glorious meal, this One Pot Creamy Cajun Chicken Pasta Recipe is going to be your new best friend. Imagine tender chicken seasoned with smoky, spicy Cajun herbs mingling with penne pasta, all cooked in a single pot to create a rich, velvety sauce loaded with the perfect balance of heat and creaminess. It’s the ideal dish for busy weeknights when you want something homemade but fuss-free, delivering a satisfying dinner without the usual mess.

Ingredients You’ll Need

A white round plate full of creamy penne pasta mixed with brownish-orange sauce and pieces of cooked chicken that are light golden brown. Bright green chopped scallions are scattered on top, adding color contrast. A black spoon is placed to the right inside the plate, slightly submerged in the pasta. The plate sits on a white marbled surface with a white and gray striped cloth partially under it. The lighting is bright, highlighting the textures of the pasta and chicken. photo taken with an iphone --ar 4:5 --v 7

This recipe relies on simple yet powerful ingredients that work harmoniously to create that irresistible Cajun flair with creamy indulgence. Each item plays a crucial role, from the bold spices that kick flavor up a notch to the creamy cheese that ties it all together in a luscious sauce.

Smoked paprika (2 tsp): Adds a deep, smoky undertone essential for authentic Cajun flavor.
Dried oregano (1 tsp): Offers a subtle herbal background that complements the spices.
Dried thyme (1 tsp): Brings an earthy aroma helping to balance the heat.
Garlic powder (1/2 tsp): Delivers a mild garlic punch that warms up the palate.
Onion powder (1/2 tsp): Enhances savory depth without overpowering.
Cayenne pepper (1/4 tsp): Adds just enough heat to make the dish lively but not overwhelming.
Black pepper (1/4 tsp): Rounds out the spice mix with a sharp bite.
Salt (1/4 tsp): Necessary to enhance all flavors beautifully.
Olive oil (1 Tbsp): Used to sear the chicken and develop flavorful crusts.
Butter (1 Tbsp): Adds richness and helps create the creamy sauce.
Boneless, skinless chicken breast (1 lb): The protein star, cubed for quick cooking and maximum tenderness.
Yellow onion (1, diced): Provides sweetness and moisture that lift the whole dish.
Penne pasta (1/2 lb, uncooked): Sturdy pasta shape that holds the sauce well and cooks perfectly in the pot.
Fire roasted diced tomatoes (15 oz): Introduces smoky, juicy flavor with a bit of acidity to cut through the cream.
Chicken broth (2 cups): The cooking liquid that infuses the pasta and chicken with savory depth.
Cream cheese (2 oz): The secret to that irresistibly smooth and creamy sauce coating every bite.
Green onions (3, sliced): For a fresh, bright finish adding both color and a mild onion crunch.

How to Make One Pot Creamy Cajun Chicken Pasta Recipe

Step 1: Mix the Cajun Seasoning and Season the Chicken

Start by combining all the spices for the Cajun seasoning in a small bowl: smoked paprika, oregano, thyme, garlic powder, onion powder, cayenne, black pepper, and salt. Cut the chicken breast into small cubes about 1/2 to 3/4 inch in size, then toss the chicken in the seasoning until every piece is well coated. This seasoning mix will build the bold flavor that makes this recipe stand out.

Step 2: Sear the Chicken

Next, heat olive oil and butter in a large, deep skillet over medium-high heat until hot and the butter is melted and foamy. Add the seasoned chicken cubes and cook them just until the outside gets a nice golden color—about a few minutes per side. Don’t worry about cooking the chicken all the way through here; this step is to lock in flavor and give a lovely texture.

Step 3: Add Onions and Build Flavor

Throw the diced yellow onion into the skillet with the chicken and cook for about 2 minutes, stirring occasionally. As the onion softens, its moisture will help lift any tasty browned bits stuck to the pan, adding depth to the flavor base of your dish.

Step 4: Combine Pasta, Tomatoes, and Broth

Now pour in the uncooked penne pasta, fire roasted diced tomatoes with their juices, and chicken broth. Give everything a good stir to mix evenly. Cover the pot with a lid and bring the liquid up to a boil. This is where the magic happens—pasta cooks right in the flavorful liquid, absorbing all the delicious spices and tomato juices.

Step 5: Simmer to Perfection

Once boiling, reduce the heat to medium-low and let the pasta simmer for about 10 minutes. Be sure to stir every couple of minutes so the pasta cooks evenly and the sauce thickens nicely without sticking. You’re aiming for tender pasta enveloped in a thick, saucy base.

Step 6: Finish with Cream Cheese and Green Onions

Finally, drop chunks of cream cheese into the skillet and stir it in until it melts, creating a rich, creamy sauce that hugs every piece of pasta and chicken. Sprinkle freshly sliced green onions on top for a burst of color and a hint of fresh onion flavor, and your one pot creamy Cajun chicken pasta is ready to enjoy!

How to Serve One Pot Creamy Cajun Chicken Pasta Recipe

A silver pan filled with cooked penne pasta mixed with pieces of light brown cooked chicken and a creamy light brown sauce, all sprinkled with chopped green onions. A wooden spoon is placed inside the pan on the right side. The pan is set on a white marbled surface. photo taken with an iphone --ar 4:5 --v 7

Garnishes

The green onions added at the end are ideal for a fresh crunch, but you can also sprinkle some freshly chopped parsley or a little grated Parmesan if you want an extra layer of flavor and visual appeal. A dash of extra cayenne or smoked paprika on top can enhance the spice level and presentation dramatically.

Side Dishes

This creamy, flavorful pasta is quite hearty on its own, but if you want to round out your meal, consider pairing it with a simple green salad dressed with a tangy vinaigrette to cut through the richness. Garlic bread or crusty French bread is also the perfect mop for any remaining sauce on your plate, making every bite count.

Creative Ways to Present

For a fun dinner party, serve your One Pot Creamy Cajun Chicken Pasta Recipe in individual deep bowls and garnish each with a sprig of fresh thyme or a lemon wedge for a hint of zest. You can also offer hot sauce on the side for guests who like an extra kick. The rustic one-pot charm looks great when plated with a sprinkle of herbs or a drizzle of olive oil for that restaurant-quality touch.

Make Ahead and Storage

Storing Leftovers

If you find yourself with leftovers, store the creamy Cajun chicken pasta in an airtight container in the refrigerator. It will keep well for up to 3 days. The flavors actually deepen a bit overnight, making reheated portions even better.

Freezing

This dish is best enjoyed fresh, but if you want to freeze some, allow it to cool completely before transferring to a freezer-safe container or bag. It should hold up well for about 1 month. When reheating, be aware the texture may change slightly, especially with the cream cheese sauce.

Reheating

Reheat your leftovers gently on the stovetop over low heat or in the microwave, stirring often. If the sauce seems too thick or dry, add a splash of chicken broth or water to bring back that creamy consistency without drying out your pasta.

FAQs

Can I use a different type of pasta for this recipe?

Absolutely! While penne works perfectly to hold the sauce, other sturdy pastas like rigatoni, fusilli, or rotini will also do great. Avoid delicate pastas like angel hair since they might overcook during the simmering step.

Is this dish very spicy?

The spice level is moderate with a nice balanced warmth from the cayenne and smoked paprika. If you prefer it milder, reduce the cayenne; for more heat, feel free to add extra or top with hot sauce.

Can I make this recipe vegetarian?

You can swap out the chicken for hearty vegetables like mushrooms or zucchini and use vegetable broth instead of chicken broth. The creamy Cajun sauce will still be flavorful and comforting.

What can I substitute for cream cheese?

If you don’t have cream cheese, try using heavy cream or half-and-half with a bit of grated Parmesan to create a creamy sauce. The texture and flavor will differ slightly, but it will still be delicious.

Do I have to season the chicken separately, or can I add all spices at once?

Seasoning the chicken first with the Cajun mix ensures every bite is well coated with flavor. You could add some spices to the cooking liquid as well for more depth, but tossing the chicken in the spices at the start is key to achieving that signature Cajun kick.

Final Thoughts

If you need a meal that combines convenience, boldness, and creamy satisfaction without a mountain of dishes, the One Pot Creamy Cajun Chicken Pasta Recipe is a must-try. It’s a recipe that transforms simple pantry ingredients into a feast bursting with Southern charm and rich textures you’ll want to make again and again. Go ahead and give it a whirl—you’ll be amazed how quickly this dish becomes a favorite in your weeknight rotation!